Tsealine Pharmatech Co., Ltd

Product name

2-Amino-3-fluorobenzoic acid

CAS NO.

825-22-9

Purity

98% min

Molecular formula

C₇H₆FNO₂

Molecular weight

155.126

White to light yellow crystal powder

Property

Purity 98% min, White to light yellow crystal powder, melting point 171~172℃

Purpose

Used as pharmaceutical intermediate in pharmaceutical synthesis

Used as pharmaceutical intermediate in pharmaceutical synthesis

Used in photosensitive materials

package

1KG, 5KG, 25KG carton barrel

Storage

Store in light, cool, dry and ventilated place

Manufacturing method

1. Using o-fluoroaniline as raw material, it reacts with chloral hydrate and hydroxylamine hydrochloride to synthesize 2-amino derivatives, then converts to 7-fluoroisatin in concentrated sulfuric acid, and finally oxidizes with hydrogen peroxide under alkaline conditions to obtain 2-amino- 3-fluorobenzoic acid.

2. The synthesis of 2-amino-3-fluorobenzoic acid is based on 2-bromo-3-fluorobenzoic acid

Emergency procedures

1. Skin contact: Remove contaminated clothing and rinse thoroughly with plenty of flowing water

2. Eye contact: immediately open the upper and lower eyelids, rinse with plenty of flowing water and seek medical advice

3. Inhalation: Quickly leave the scene to a place with fresh air to keep the respiratory tract unobstructed. When breathing is stopped when oxygen delivery is stopped, artificial respiration should be performed immediately and seek medical attention.